|
| Status |
Public on Jan 09, 2014 |
| Title |
The Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites (ChIP-seq MEFs) |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We have mapped binding sites for the histone demethylase, Jmjd2c/Kdm4c/Gasc1, in mouse embryonic fibroblasts (MEFs) and the impact of Jmjd2c depletion on H3K9me3 and H3K36me3 distributions.
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| Overall design |
ChIP-seq was performed using antibodies recognizing Jmjd2c, H3K9me3 or H3K36me3. Chromatin was obtained from conditional Jmjd2c knockout MEFs cultured in the absence or presence of OHT to induce activation of Cre recombinase and loss of Jmjd2c expression.
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| |
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| Contributor(s) |
Pedersen MT |
| Citation(s) |
24396064 |
| Submission date |
Jan 09, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Marianne Terndrup Pedersen |
| E-mail(s) |
marianne.pedersen@bric.ku.dk
|
| Organization name |
BRIC
|
| Department |
University of Copenhagen
|
| Lab |
Kim B. Jensen
|
| Street address |
Ole Maaloes Vej 5
|
| City |
Copenhagen N |
| ZIP/Postal code |
2200 |
| Country |
Denmark |
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| Platforms (2) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (7)
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| This SubSeries is part of SuperSeries: |
| GSE28332 |
The Demethylase JMJD2C/KDM4C Localizes to H3K4me3 Positive Transcription Start Sites |
|
| Relations |
| BioProject |
PRJNA233999 |
| SRA |
SRP035262 |
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