|
| Status |
Public on Dec 31, 2013 |
| Title |
Tau promotes neurodegeneration through global chromatin relaxation |
| Organism |
Drosophila melanogaster |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We performed H3K9me2-based ChIP-seq to identify regions of the Drosophila genome that are H3K9me2-depleted due to transgenic neuronal expression of human mutant tau.
|
| |
|
| Overall design |
Examination of H3K9me2 histone methylation in 10 day old control and tau transgenic Drosophila heads.
|
| |
|
| Contributor(s) |
Frost B, Hemberg M, Feany M |
| Citation(s) |
24464041 |
| |
| Submission date |
Dec 30, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Bess Frost |
| E-mail(s) |
sefrost@partners.org
|
| Organization name |
Brigham and Women's Hospital
|
| Department |
Pathology
|
| Lab |
Mel Feany
|
| Street address |
77 Avenue Louis Pasteur
|
| City |
Boston |
| State/province |
Massachusetts |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA232714 |
| SRA |
SRP034843 |
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