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Series GSE5370 Query DataSets for GSE5370
Status Public on Jul 21, 2006
Title Myositis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Idiopathic inflammatory myopathies (polymyositis and dermatomyositis) are heterogeneous group of muscle disorders of unknown etiology.The pathogenic pathways responsible for muscle fiber damage and dysfunction in myositis are not currently well defined. Identification of such pathways may help to design novel therapeutic interventions and also help to develop diagnostic tests.
Keywords: Development or differentiation design
Overall design Muscle biopsies from a separate group of 5 adult untreated female dermatomyositis (PHM-DM samples) patients were profiled and compared to muscle tissue of normal human healthy volunteers (FSH-NHM samples) to define  molecular pathways in muscle of myositis patients. Confirm and map key pathway members to specific cell types in the muscle tissue of patients and controls using RT-PCR, Western blotting and Immunolocalization.
Contributor(s) Kanneboyina N
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Submission date Jul 21, 2006
Last update date Oct 09, 2019
Contact name Eric P Hoffman
Organization name Binghamton University - SUNY
Department Pharmaceutical Sciences
Street address PO Box 6000
City Binghamton
State/province NY
ZIP/Postal code 13902
Country USA
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (9)
GSM74359 FSH-NHM-3UA-s2
GSM74360 FSH-NHM-4UA-s2
GSM118580 PHM-DM-1aUA-s2
BioProject PRJNA96267

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE5370_RAW.tar 33.4 Mb (http)(custom) TAR (of CEL)

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