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Series GSE53615 Query DataSets for GSE53615
Status Public on Dec 24, 2013
Title Gene expression signatures of HaCaT cell lines transfected with mutant TRPV3
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We identified a number of affected pathways through transcriptome analysis on the skin biopsy samples of the FPPK patients. Our findings suggest that TRPV3 dysfunction may increase apoptotic activity, inhibit keratinocyte differentiation and disturb the intricate balance between proliferation and differentiation state of keratinocytes in the skin.
 
Overall design To understand the effect of TRPV3 mutation, transcriptome of HaCaT cell lines transfected with mutant TRPV3 were profiled in time-course manner (16, 24 and 40hr).
 
Contributor(s) He Y, Wang K
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Submission date Dec 23, 2013
Last update date Jan 09, 2018
Contact name Ji-Hoon Cho
E-mail(s) jcho@systemsbiology.org
Organization name Institute for Systems Biology
Street address 401 Terry Avenue North
City Seattle
State/province WA
ZIP/Postal code 98109
Country USA
 
Platforms (1)
GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
Samples (6)
GSM1296896 HaCaT_16hr_Control
GSM1296897 HaCaT_24hr_Control
GSM1296898 HaCaT_40hr_Control
This SubSeries is part of SuperSeries:
GSE53616 Gene expression signatures in the skin of focal palmoplantar keratoderma (FPPK) patients, and cell lines transfected with mutant TRPV3
Relations
BioProject PRJNA232486

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE53615_RAW.tar 74.4 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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