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Series GSE53292 Query DataSets for GSE53292
Status Public on Jan 01, 2016
Title Transcriptomic analysis of Plasmodium PBANKA, PBSLTRiP-KO, PB268-KO parasite infected and uninfected host cell
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Liver stage of malaria parasite exports SLTRiP and PB268 to the cytosol of parasite infected host cell. To know the host genes perturbed by WT-PBANKA, SLTRiP-KO and PB268-KO parasite growth, we did transcriptomic sequencing of infected host cells. We did mRNA sequencing of four samples for comparative analysis of WT and PB-knockout parasites infected host cells at 22 hours of post sporozoites infection.
Overall design mRNA profiles of Plasmodium PBANKA, PBSLTRiP-KO, PB268-KO parasite infected and uninfected HepG2 cells after 22hrs of sporozoites infections were generated by deep sequencing using Illumina GAIIx.
Contributor(s) Jaijyan DK, Pandit A, Singh AP
Citation(s) 25960542
Submission date Dec 13, 2013
Last update date May 15, 2019
Contact name Agam Prasad Singh
Organization name NII
Department IDL
Street address Aruna Asaf Ali Marg
City New Delhi
State/province Delhi
ZIP/Postal code 110067
Country India
Platforms (1)
GPL10999 Illumina Genome Analyzer IIx (Homo sapiens)
Samples (4)
GSM1289018 HepG2-PBSLTRiP-KO-mRNA Sequencing
GSM1289019 HepG2-PB268-KO-mRNA Sequencing
GSM1289020 HepG2- PBANKA-WT-mRNA Sequencing
BioProject PRJNA231615
SRA SRP034011

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE53292_RAW.tar 310.0 Kb (http)(custom) TAR (of TXT)
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Raw data are available in SRA
Processed data provided as supplementary file

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