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Series GSE53213 Query DataSets for GSE53213
Status Public on Mar 31, 2014
Title Expression data from glioma cells exposed to interferon (IFN)-beta
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Glioma cells are sensitized to the alkylator temozolomide after exposure to IFN-beta. In glioma-initiating cells (GIC), IFN-beta alone reduces clonogenicity. We investigated differentially expressed genes with or without IFN exposure in either longterm glioma cells or GIC.
We used microarrays to investigate differential gene regulation in glioma cells after exposure to either ddH20 or IFN-beta 300 IU/ml at 6 h or 24 h.
Overall design We used either the longterm cell line LNT-229 or the GIC cell lines GS-2 and GS-9 and exposed them to either IFN-beta 300 IU/ml or ddH20 for 6 h or 24 h.
Contributor(s) Happold C, Silginer M, Florea AM, Deenen R
Citation(s) 24526161, 26441059
Submission date Dec 11, 2013
Last update date Mar 16, 2021
Contact name Karl Koehrer
Organization name University of Duesseldorf
Department BMFZ
Street address Universitaetsstr. 1
City Duesseldorf
ZIP/Postal code 40225
Country Germany
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (12)
GSM1287751 LNT-229_Ctrl_6h_rep1
GSM1287752 LNT-229_IFNb300_6h_rep1
GSM1287753 LNT-229_Ctrl_24h_rep1
BioProject PRJNA231124

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Supplementary file Size Download File type/resource
GSE53213_RAW.tar 22.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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