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| Status |
Public on Dec 04, 2013 |
| Title |
miRNA expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study2] |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human betaherpesvirus 5; Murid betaherpesvirus 1; human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Human gammaherpesvirus 8; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Using a PTSD mouse model, we investigated the longitudinal transcriptomic changes in heart tissues after the exposure to stress through intimidation
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| Overall design |
We designed our time-course study (Study II) with three experimental conditions where we varied the length of time that subservient mice were exposed to aggressor mice with the same length of rest time after the exposure (1day). The conditions included were 1day-exposure (T1R1), 2day-exposure (T2R1) and 3day-exposure (T3R1).
We designed our initial study (Study I) with four experimental conditions where we varied the length of time that subservient mice were exposed to aggressor mice and the length of rest time after the exposure. The conditions included were short exposure-short rest (T5R1-T indicates the number of days of trauma exposure; R indicates the number of days of rest after exposure), short exposure-long rest (T5R10), long exposure-short rest (T10R1) and long exposure-long rest (T10R42)
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| Contributor(s) |
Wang K, Lee I, Cho J, Hammamieh R, Baxter D, Scherler K, Etheridge A, Yuan Y, McClarty S, Kulchenko A, Gautam A, Muhie S, Chakraborty N, Jett M, Galas DJ, Hood L |
| Citation(s) |
24516145 |
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| Submission date |
Dec 02, 2013 |
| Last update date |
May 10, 2016 |
| Contact name |
Ji-Hoon Cho |
| E-mail(s) |
jcho@systemsbiology.org
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| Organization name |
Institute for Systems Biology
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| Street address |
401 Terry Avenue North
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| City |
Seattle |
| State/province |
WA |
| ZIP/Postal code |
98109 |
| Country |
USA |
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| Platforms (1) |
| GPL11434 |
miRCURY LNA microRNA Array, 6th generation - hsa, mmu & rno |
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| Samples (16)
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| This SubSeries is part of SuperSeries: |
| GSE52875 |
Expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) |
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| Relations |
| BioProject |
PRJNA230438 |
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