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Series GSE52826 Query DataSets for GSE52826
Status Public on Nov 03, 2014
Title the whole-genome methylation profile of esophageal squamous cell carcinoma
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Both genetic and epigenetic aberrations are linked by intricate crosstalk, and can either individually or in synergy lead to the development of cancer. Accumulating evidence suggests that epigenetic changes such as alterations in DNA methylation play a crucial role in ESCC. We performed a Illumina Infinium HumanMethylation450 BeadChip to examine the global methylation signature of esophageal squamous cell carcinoma of Chinese patients.
Overall design DNA methylation profiles of esophageal squamous cell carcinoma (4 samples), paired adjacent normal surrounding tissues (4 samples) and normal esophagus mucosa from healthy individuals (4 samples) were generated using Infinium methylation 450K BeadChips from Illumina (Illumina, San Diego, USA).
Contributor(s) Li XF, Jiang CY, Zhang JR, Zheng YF
Citation(s) 25050929
Submission date Nov 29, 2013
Last update date Mar 22, 2019
Contact name xufeng li
Phone +8615018731689
Organization name Southern Medical University
Department oncology center of zhujiang hospital
Street address gongye avenue 253
City guangzhou
State/province guangdong
ZIP/Postal code 510282
Country China
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (12)
GSM1276745 genomic DNA from sample T1
GSM1276746 genomic DNA from sample T2
GSM1276747 genomic DNA from sample T3
BioProject PRJNA230249

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52826_RAW.tar 183.1 Mb (http)(custom) TAR
GSE52826_signal_intensities.txt.gz 51.0 Mb (ftp)(http) TXT
Processed data included within Sample table

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