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Series GSE52788 Query DataSets for GSE52788
Status Public on Nov 22, 2014
Title DNA copy number changes in malignant mesothelioma
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
SNP genotyping by SNP array
Summary Malignant mesothelioma (MM) is an asbestos-related malignancy. Discrimination between MM and reactive mesothelial hyperplasia (RM) is often difficult. MM cells have a broad histological spectrum, and consist mainly of epithelioid, sarcomatoid, and biphasic cell types. The prognosis of MM is generally poor, but better prognosis has been reported with the epithelioid type of MM than the non-epithelioid type. We applied a genome-wide analysis to the identification of new markers that may aid in differentiating the epithelioid type of MM from other histological types and from RM cells.
Overall design Array-based comparative genomic hybridization analysis was performed on malignant mesothelioma (MM) primary cell cultures, reactive mesothelial hyperplasia (RM) primary cell cultures; early passage of in vitro primary cell cultures to minimize acquisition of additional genomic changes. If available, matched peripheral blood was applied to analysis.
Contributor(s) Yoshikawa Y, Hashimoto-Tamaoki T
Citation(s) 24916674
Submission date Nov 27, 2013
Last update date Nov 27, 2018
Contact name Yoshie Yoshikawa
Phone +81-798-45-6587
Organization name Hyogo College of Medicine
Department Genetics
Street address 1-1 Mukogawa-cho
City Nishinomiya
State/province Hyogo
ZIP/Postal code 663-8501
Country Japan
Platforms (3)
GPL3718 [Mapping250K_Nsp] Affymetrix Mapping 250K Nsp SNP Array
GPL3720 [Mapping250K_Sty] Affymetrix Mapping 250K Sty2 SNP Array
GPL6801 [GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array
Samples (34)
GSM1275963 patient 16_malignant mesothelioma_250Knsp
GSM1275964 patient 19_peripheral blood_250Knsp
GSM1275965 patient 19_reactive mesothelial cells_250Knsp
BioProject PRJNA230026

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52788_RAW.tar 916.7 Mb (http)(custom) TAR (of CEL, CHP)
GSE52788_SNP6_summary.txt.gz 22.7 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data provided as supplementary file

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