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Series GSE52633 Query DataSets for GSE52633
Status Public on Oct 21, 2014
Title MicroRNA Marker Based Prognostication of Oral Squamous Cell Carcinoma
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary The aim of our study was to discover a miR marker panel prognostic of 5-year survival in OSCC patients that may be utilized in parallel with the current clinical covariates. We assessed differential expression of miRNAs genome-wide via deep sequencing in 20 tumor tissue samples. We also attempted to identify deregulated miR expression signatures that may serve as the prognostic marker of cancer survival. Selected miR marker-based panel then may serve as a guide for selection of appropriate follow-up chemo/radiation treatment, significantly improving the clinical management of OSCC and the overall survival rate.
Overall design Identify miRs differentially expressed in the poor prognosis group compared to the good prognosis group
Contributor(s) Yoon AJ, Robine N
Citation(s) 25360222
Submission date Nov 21, 2013
Last update date May 15, 2019
Contact name Angela Yoon
Organization name Columbia University Medical Center
Street address 630 West 168th Street, PH15W-1562
City New York
State/province NY
ZIP/Postal code 10032
Country USA
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (20)
GSM1273054 Oral Cancer Favorable 5-year survival Y001
GSM1273055 Oral Cancer Favorable 5-year survival Y002
GSM1273056 Oral Cancer Favorable 5-year survival Y003
BioProject PRJNA229505
SRA SRP033248

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52633_miraligner_Count_matrix.txt.gz 33.0 Kb (ftp)(http) TXT
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Processed data are available on Series record

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