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Series GSE52038 Query DataSets for GSE52038
Status Public on Nov 05, 2013
Title 5'RNA-seq analysis of hypertrophic cardiomyopathy (HCM) in mice that carry a human missence mutation in the myosin heavy chain
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We developed a 5'RNA-seq methodology to concurrently assess gene expression and start-site usage changes. We applied this methodology to study hypertrophic cardiomyopathy in mice harboring a human deleterious mutation.
Overall design 5'RNA-seq analysis of transcriptomes from mouse hearts with or without hypertrophic cardiomyopathy. Biological replicates were pooled into a single sequencing run. 5'RNA-seq methodology consists of enhanced sequencing of 5' ends and computational assessment of changes at start-sites of genes.
Contributor(s) Seidman J
Citation(s) 24509080
Submission date Nov 04, 2013
Last update date May 15, 2019
Contact name Jonathan Seidman
Organization name Harvard Medical School
Department Genetics
Lab Seidman
Street address 77 Avenue Louis Pasteur, NRB256
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (2)
GSM1257900 WT
GSM1257901 MHC403
BioProject PRJNA226563
SRA SRP032512

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE52038_Supplementary-table-1-date11021.txt.gz 1.8 Mb (ftp)(http) TXT
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Processed data are available on Series record

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