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Series GSE51507 Query DataSets for GSE51507
Status Public on Oct 22, 2013
Title Comparison of microRNA Profiling Platforms (HTS)
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Global miRNA expression profiling of human malignancies is gaining popularity in both basic and clinically driven research. But to date, the majority of such analyses have used microarrays and quantitative real-time PCR. With the introduction of digital count technologies, such as next-generation sequencing (NGS) and the NanoString nCounter System, we have at our disposal, many more options. To make effective use of these different platforms, the strengths and pitfalls of several miRNA profiling technologies were assessed, including a microarray platform, NGS technologies and the NanoString nCounter System. These results were compared to gold-standard quantitative real-time PCR.
Overall design Comparison of non-small cell lung cancer cell lines grown in vitro (n = 5) and in vivo (n = 5) as xenograft models.
Contributor(s) Tam S, de Borja R, Tsao M, McPherson JD
Citation(s) 24445778
Submission date Oct 21, 2013
Last update date May 15, 2019
Contact name Shirley Tam
Organization name Ontario Institute for Cancer Research
Department Genome Technologies
Street address 661 University Avenue, Suite 510, MaRS Building, West Tower
City Toronto
State/province Ontario
ZIP/Postal code M5G 0A3
Country Canada
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (10)
GSM1246702 Lung Cancer Cell Line A549
GSM1246703 Lung Xenograft A549
GSM1246704 Lung Cancer Cell Line H460
This SubSeries is part of SuperSeries:
GSE51508 Comparison of microRNA Profiling Platforms
BioProject PRJNA223326
SRA SRP031698

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE51507_RAW.tar 110.0 Kb (http)(custom) TAR (of TXT)
GSE51507_linear_scaled_counts.txt.gz 17.9 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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