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Series GSE5117 Query DataSets for GSE5117
Status Public on Jun 21, 2007
Title Wilms' tumor 1 WT1(-KTS) isoform time course induction in U2OS cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary The Wilms' tumor suppressor gene (WT1) encodes a zinc finger transcription factor that plays important roles during development of several organs including metanephric kidneys. A number of WT1 target genes have been identified, but the detailed mechanisms by which WT1 orchestrates renal development remain elusive. To identify WT1 target genes relevant to development, genome-wide expression profiling was performed using oligonucleotide microarrays representing 39,000 human transcripts
Keywords: Wilms' tumor 1 (WT1) gene, -KTS isoform; time course
Overall design Sample_source_name: UB27 cells, U2OS cells with Tetracycline-repressible WT1(-KTS) expression

Sample_characteristics: U2OS cell line (osteosarcoma; female), Tetracycline-repressible WT1(-KTS) expression, time-course induction
of WT1(-KTS) expression

Sample_description: WT1(-KTS) expression was induced for 4, 8 or 12
hrs and the expression profile of each time-points was compared to the
uninduced sample (0 hr).
Contributor(s) KIM H, Kim M, Cam M, Malik K, Lee S
Citation(s) 17430890
Submission date Jun 21, 2006
Last update date Aug 10, 2018
Contact name WeiPing Chen
Phone 301-496-0175
Organization name NIDDK/NIH
Department GCL
Lab Genomics Core Lab
Street address Bldg 8, Room 1A11, NIDDK/NIH
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (4)
GSM115522 WT1(-KTS) expression induced for 12 hrs 01-14-03_Lee_U133A_12_2
GSM115523 WT1(-KTS) expression induced for 4 hrs 01-14-03_Lee_U133A_4_2
GSM115524 WT1(-KTS) expression induced for 8 hrs 01-14-03_Lee_U133A_8_2
BioProject PRJNA96611

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