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Series GSE50774 Query DataSets for GSE50774
Status Public on May 27, 2014
Title DNA methylation alteration and gene expression sigature in brainstem, thalamic, and supratentorial gliomas
Organism Homo sapiens
Experiment type Expression profiling by array
Methylation profiling by array
Summary Gliomas arising in the brainstem and thalamus are devastating tumors that are difficult to surgically resect due to their proximity to eloquent brain structures. Here, we performed a comprehesive genomic and epigenomic study, using gene expression and methylation microarrays, to research on th different genomic and epigenetic signatures between brainstem, thalamic, and supratentorial gliomas.
Overall design Comparison of brainstem, thalamic and supratentorial gliomas
Contributor(s) Zhang L, Chen LH, Wan H, Zhou W, Feng J, Yang S, Jones S, Yang R, Killela PJ, Zhang J, Wu Z, Li G, Hao S, Wang Y, Webb JB, McLendon RE, He Y, Reitman ZJ, Bigner DD, Yan H
Citation(s) 24880341
Submission date Sep 11, 2013
Last update date Mar 25, 2019
Contact name Hai Yan
Organization name Duke University
Department Pathology
Lab Yan Lab
Street address 199B-MSRB, Research Drive
City Durham
State/province NC
ZIP/Postal code 27710
Country USA
Platforms (2)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (66)
GSM1228941 brain tumor 243
GSM1228942 brain tumor 248
GSM1228943 brain tumor 249
BioProject PRJNA218881

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50774_Matrix_signal_intensities_09102013.txt.gz 107.2 Mb (ftp)(http) TXT
GSE50774_RAW.tar 282.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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