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Series GSE50593 Query DataSets for GSE50593
Status Public on Dec 12, 2013
Title Coordinated genomic control of ciliogenesis and cell movement by Rfx2
Organism Xenopus laevis
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We have performed a systems-level analysis of the RFX/Daf-19 family transcription factor, Rfx2. Using a combination of high-throughput sequencing of Rfx2-regulated transcripts and chromosomal binding sites, we provide a comprehensive accounting of the target genes by which Rfx2 controls ciliogenesis and cilia beating in vertebrates.
 
Overall design RNA-seq: two biological replicates for control and RFX2 knockdown by morpholino injection, ChIP-seq: RFX2-GFP pulldown with GFP antibody, GFP only expression used as control
 
Contributor(s) Chung M, Kwon T, Gupta R, Baker JC, Marcotte EM, Wallingford JB
Citation(s) 24424412, 25419512
Submission date Sep 04, 2013
Last update date May 15, 2019
Contact name Taejoon Kwon
E-mail(s) tkwon@unist.ac.kr
Organization name Ulsan National Institute of Science and Technology
Department Department of Biomedical Engineering
Street address 50 Unist-gil
City Ulsan
ZIP/Postal code 44919
Country South Korea
 
Platforms (1)
GPL17682 Illumina HiSeq 2000 (Xenopus laevis)
Samples (6)
GSM1224372 Ctrl_1
GSM1224373 Ctrl_2
GSM1224374 RFX2KD_1
Relations
BioProject PRJNA218018
SRA SRP029582

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50593_Chung201208_XENLA_ChIP_RFX2_peaks.txt.gz 649.1 Kb (ftp)(http) TXT
GSE50593_SuppTable2.RFX2_rnaseq_chip.2012oct.txt.gz 982.0 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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