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| Status |
Public on May 29, 2014 |
| Title |
Trophoblast giant cell underrepresentation (sequencing) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We characterized the mouse trophoblast giant cell epigenome and gene expression profiles. We then compared these data to our data on underrepresentation in the polyploid trophoblast giant cells.
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| Overall design |
We profiled 5 histone modifications (+ chromatin input) using ChIP-Seq, and digital expression profiles (3' RNA-Seq) for trophoblast giant cells derived from mouse. Furthermore, we profiled digital expression profiles (3' RNA-Seq) for in vivo trophoblast giant cells samples from e9.5 wildtype mouse trophoblast giant cells. We found that underrepresented domains in trophoblast giant cells are enriched for repressive marks and anti-correlate with active marks and transcription.
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| |
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| Contributor(s) |
Chuong EB, Hannibal RL, Baker JC |
| Citation(s) |
24785991 |
| Submission date |
Sep 03, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Roberta L Hannibal |
| E-mail(s) |
robertah@stanford.edu
|
| Organization name |
Stanford University
|
| Department |
Genetics
|
| Street address |
300 Pasteur Drive
|
| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (18)
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| This SubSeries is part of SuperSeries: |
| GSE50585 |
Trophoblast giant cell underrepresentation |
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| Relations |
| BioProject |
PRJNA218198 |
| SRA |
SRP029516 |
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