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| Status |
Public on Aug 13, 2013 |
| Title |
Expression data from five primary human glioblastomas (frozen surgical resection) and one non-neoplastic adult brain (frozen autopsy tissue) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
DNA hypomethylation could lead to activation of alternate promoters in GBM. We profiled DNA methylation and H3K4me3 genome-wide, and also performed expression and copy number analysis on the same samples
In this dataset, we include all expression data obtained for five GBMs and one normal brain. We identified loci with concurrent DNA hypomethylation and H3K4me3 in GBM, and analyzed expression of the nearest gene in the same sample using these data
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| |
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| Overall design |
Six total samples were analyzed. Each GBM sample was compared to normal brain to obtain expression changes
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| |
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| Contributor(s) |
Nagarajan RP, Costello JF |
| Citation(s) |
24709822 |
| |
| Submission date |
Jul 31, 2013 |
| Last update date |
Jun 02, 2014 |
| Contact name |
RAMAN PAUL NAGARAJAN |
| Organization name |
UCSF
|
| Department |
NEUROSURGERY
|
| Lab |
COSTELLO
|
| Street address |
1450 3RD ST, ROOM HD200
|
| City |
SAN FRANCISCO |
| State/province |
CA |
| ZIP/Postal code |
94158 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL15648 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [HuGene10stv1_Hs_ENTREZG version 13.0.0] |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE49810 |
Expression and copy number data from five primary human glioblastomas |
|
| Relations |
| BioProject |
PRJNA214968 |
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