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| Status |
Public on May 30, 2014 |
| Title |
Large-scale multi-species survey of metabolome and lipidome |
| Organisms |
Macaca mulatta; Pan troglodytes; Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This dataset was generated with the goal of comparative study of gene expression in three brain regions and two non-neural tissues of humans, chimpanzees, macaque monkeys and mice. Using this dataset, we performed studies of gene expression and gene splicing evolution across species and search of tissue-specific gene expression and splicing patterns. We also used the gene expression information of genes encoding metabolic enzymes in this dataset to support a larger comparative study of metabolome evolution in the same set of tissues and species.
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| Overall design |
120 tissue samples of prefrontal cortex (PFC), primary visual cortex (VC), cerebellar cortex (CBC), kidney and skeletal muscle of humans, chimpanzees, macaques and mice.
The data accompanies a large set of metabolite measurements of the same tissue samples. Enzyme expression was used to validate metabolite measurement variation among species.
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| Contributor(s) |
Jieyi X, Xi J, Bozek K, Khaitovich P |
| Citation(s) |
24866127 |
| |
| Submission date |
Jul 30, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Jieyi Xiong |
| Organization name |
VIB-KULeuven Center for Cancer Biology
|
| Street address |
Herestraat 49, box 912
|
| City |
Leuven |
| ZIP/Postal code |
3000 |
| Country |
Belgium |
| |
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| Platforms (4)
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| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL14954 |
Illumina HiSeq 2000 (Macaca mulatta) |
| GPL16809 |
Illumina HiSeq 2000 (Pan troglodytes) |
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| Samples (120)
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| Relations |
| BioProject |
PRJNA213747 |
| SRA |
SRP028336 |
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