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Series GSE48878 Query DataSets for GSE48878
Status Public on Dec 03, 2013
Title In vivo transcriptional goverance of hair follicle stem cells by canonical Wnt regulators
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by hair follicle stem cells (HFSCs). HFSCs regenerate hair in response to canonical Wnt signalling. We used RNA-seq to unfold genome-wide chromatin landscapes of β-catenin within the native HFSC-niche.
Overall design β-catenin control and cKO hair follicle stem cells (HFSCs) at the onset of anagen skins were FACS-purified for RNA-sequcencing.

Telogen quiescent hair follicle stem cells (HFSCs) were FACS-purified for ChIP-sequcencing.

Telogen>anagen activated bulge hair follicle stem cells (HFSCs) were FACS-purified for RNA-sequcencing.
Contributor(s) Lien W, Fuchs E
Citation(s) 24282298, 24463605
Submission date Jul 15, 2013
Last update date May 15, 2019
Contact name Wen-Hui Lien
Phone 212-327-7482
Organization name The Rockefeller Unoversity
Department Mammalian cell biology and development
Lab Elaine Fuchs
Street address 1230 York Ave Box#300
City New York
State/province NY
ZIP/Postal code 10065
Country USA
Platforms (2)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (8)
GSM1186241 β-cat Het
GSM1186242 β-cat cKO
GSM1187391 qHFSC_input DNA
BioProject PRJNA212099
SRA SRP027384

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE48878_RAW.tar 562.2 Mb (http)(custom) TAR (of WIG)
GSE48878_RNA-seq_Matrix_Table.txt.gz 826.2 Kb (ftp)(http) TXT
GSE48878_axin_M_FPKM.txt.gz 623.6 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
Processed data provided as supplementary file

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