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| Status |
Public on Feb 19, 2014 |
| Title |
Uniform response to aneuploidy in human cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
There are many different types and origins of aneuploidy, but whether there is a uniform cellular response to aneuploidy in human cells has not been addressed so far. To uncover a uniform transcriptional response to aneuploidy we evaluted the transcription profiles of trisomic and tetrasomic cell lines and cell lines with complex aneuploid karyotypes.
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| Overall design |
mRNA expression analysis of aneuploid cell lines derived from HCT116 compared to the HCT116 diploid cell line. With the exception of HCT116 3/3, three biological replicates of the Microarray experiment were performed.
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| Contributor(s) |
Dürrbaum M, Kuznetsova AY, Passerini V, Stingele S, Stoehr G, Storchová Z |
| Citation(s) |
24548329, 25205676 |
| Submission date |
Jun 11, 2013 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Milena Dürrbaum |
| Organization name |
Max Planck Institute of Biochemistry
|
| Department |
Maintenance of Genome Stability
|
| Street address |
Am Klopferspitz 18
|
| City |
Martinsried |
| ZIP/Postal code |
82152 |
| Country |
Germany |
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| Platforms (2) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
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| Samples (14)
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| Relations |
| BioProject |
PRJNA208051 |
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