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| Status |
Public on Sep 25, 2013 |
| Title |
Differentially expressed genes by anti tumor treatment in human cancer cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To identify differentially expressed genes by anti cancer treatments (microRNAs, siRNAs and chemical compounds) in human cancer, several cell lines (prostate cancer, renal cell carcinoma and head and neck squamous cell carcinoma) were subjected to Agilent whole genome microarrays.
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| Overall design |
Human cancer cell lines (PC3, DU145, LNCap, A498, 786-O, FaDu and SAS) were treated with miRNAs (miR-145, miR-375, miR-23b, miR-24, miR-27b and miR-29a), siRNAs (si-CAV2, si-LAMB3 and si-GOLM1) and chemical compunds (genistein, wogonin and CXCL10).
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| Contributor(s) |
Seki N |
| Citation(s) |
23936419, 24091622, 25115396, 29423074 |
| Submission date |
Jun 05, 2013 |
| Last update date |
Jun 28, 2019 |
| Contact name |
Naohiko Seki |
| E-mail(s) |
naoseki@faculty.chiba-u.jp
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| Phone |
+81-43-226-2971
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| Organization name |
Chiba University
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| Department |
Functional Genomics
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| Street address |
1-8-1, Inohana
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| City |
Chiba |
| State/province |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
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| Platforms (2) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
| GPL16699 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
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| Samples (24)
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| GSM1154153 |
Differentially expressed genes by genistein treatment in PC3 |
| GSM1154154 |
Differentially expressed genes by genistein treatment in DU145 |
| GSM1154157 |
Differentially expressed genes by knocking down of CAV2 in A498 |
| GSM1154159 |
Differentially expressed genes by knocking down of CAV2 in 786O |
| GSM1154161 |
Identification of miR-145 target genes in PC3 |
| GSM1154163 |
Identification of miR-145 target genes in DU145 |
| GSM1154165 |
Identification of miR-145 target genes in LNCap |
| GSM1154167 |
Identification of miR-375 target genes in FaDu |
| GSM1154169 |
Differentially expressed genes by knocking down of LAMB3 in FaDu |
| GSM1154171 |
Differentially expressed genes by knocking down of LAMB3 in SAS |
| GSM1154174 |
Differentially expressed genes by wogonin treatment in SAS |
| GSM1154176 |
Differentially expressed genes by wogonin treatment in FaDu |
| GSM1154178 |
Identification of miR-23b target genes in PC3 |
| GSM1154180 |
Identification of miR-24 target genes in PC3 |
| GSM1154182 |
Identification of miR-27b target genes in PC3 |
| GSM1154184 |
Identification of miR-29a target genes in SAS |
| GSM1154186 |
Identification of miR-143 target genes in DU145 |
| GSM1154188 |
Identification of miR-143 target genes in PC3 |
| GSM1154190 |
Differentially expressed genes by knocking down of GOLM1 in DU145 |
| GSM1154191 |
Differentially expressed genes by knocking down of GOLM1 in PC3 |
| GSM1154192 |
Identification of miR-27b target genes in 786O |
| GSM1154193 |
Identification of miR-27b target genes in A498 |
| GSM1154194 |
Differentially expressed genes 12h after CXCL10 treatment in 786O |
| GSM1154195 |
Differentially expressed genes 24h after CXCL10 treatment in 786O |
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| Relations |
| BioProject |
PRJNA207084 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE47657_RAW.tar |
507.9 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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