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Series GSE47536 Query DataSets for GSE47536
Status Public on Feb 03, 2015
Title Global gene expression in the adult Gata6 null mouse pancreas
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We report the global gene expression of mouse pancreatic cells in a pancreas-specific conditional knock-out mouse for Gata6, as compared with age-matched controls. Total RNA was extracted from the pancreas of 6-8 -week old mice of the two genotypes and analyzed. at this age, Gata6P-/- pancreata are histologically normal, but the acinar differentiation programme is already altered. we observe that loss of Gata6 causes the de-repression of ectopic non-pancreatic genes, as well as some genes involved in the mesenchymal programme.
Overall design mRNA extracted from the pancreas of 4 controls and 4 Gata6P-/- mice was sequenced.
Contributor(s) Martinelli P, Carrillo de Santa Pau E, Real FX
Citation(s) 25596178
Submission date May 30, 2013
Last update date May 15, 2019
Contact name Enrique Carrillo de Santa Pau
Organization name Spanish National Cancer Research Centre (CNIO)
Department Cancer Cell Biology Programme
Lab Epithelial Carcinogenesis group
Street address C/ Melchor Fernández Almagro, 3
City Madrid
ZIP/Postal code 28029
Country Spain
Platforms (1)
GPL11002 Illumina Genome Analyzer IIx (Mus musculus)
Samples (8)
GSM1151696 BKD244P_WT
GSM1151697 ASK210_WT
GSM1151698 ASK212
This SubSeries is part of SuperSeries:
GSE47537 Gata6
BioProject PRJNA205991
SRA SRP023469

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE47536_RAW.tar 8.0 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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