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| Status |
Public on Jul 27, 2006 |
| Title |
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. We report the identification and biologic characterization of an LPS-like molecule extracted from the cyanobacterium Oscillatoria Planktothrix FP1 (CyP).
Keywords: different ligands
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| Overall design |
2 untreated (CTR), 2 treated with LPS at 3h, 2 treated with CyP at 1h, 2 treated with CyP at 3h, 2 treated with LPS + CyP at 3h
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| |
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| Contributor(s) |
Maccagno A, Monica M, Rinaldi A, Bertoni F, Lanzavecchia A, Carlo R, Sallusto F |
| Citation(s) |
16717116 |
| Submission date |
May 01, 2006 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Francesco Bertoni |
| E-mail(s) |
francesco.bertoni@ior.usi.ch
|
| Phone |
+41 91 820 0367
|
| Organization name |
IOR
|
| Department |
Lymphoma & Genomics Research Program
|
| Street address |
Via V. Vela 6
|
| City |
Bellinzona |
| State/province |
Ticino |
| ZIP/Postal code |
6500 |
| Country |
Switzerland |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (10)
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| Relations |
| BioProject |
PRJNA95695 |
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