|
| Status |
Public on Apr 29, 2014 |
| Title |
Contribution of CBX4 to cumulus oophorus cell phenotype in mice, and attendant effects in cumulus cell cloned embryos |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Cumulus oophorus cells play an essential role in oocyte development. CBX4 is a member of the Polycomb complex, which plays a role in regulating cellular differentiation.
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| |
|
| Overall design |
We used siRNA mediated knockdown of Cbx4 expression followed by Affymetrix array analysis to evaluate the role of CBX4 in cumulus cell differentiated state.
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| |
|
| Contributor(s) |
Latham KE, Hao L, Midic U, Garriga J |
| Citation(s) |
24280258 |
| |
| Submission date |
May 01, 2013 |
| Last update date |
Jun 19, 2014 |
| Contact name |
Uros Midic |
| E-mail(s) |
uros@msu.edu
|
| Organization name |
Michigan State University
|
| Department |
Animal Sciences
|
| Lab |
Latham lab
|
| Street address |
474 S. Shaw Lane
|
| City |
East Lansing |
| State/province |
MI |
| ZIP/Postal code |
48824-1225 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17109 |
Affymetrix GeneChip Mouse Genome 430 2.0 Array [CDF: Mouse430_2_custom] |
|
| Samples (7)
|
| GSM1132529 |
Scrambled siRNA control cumulus cells, biological rep. 1 |
| GSM1132530 |
Scrambled siRNA control cumulus cells, biological rep. 2 |
| GSM1132531 |
Scrambled siRNA control cumulus cells, biological rep. 3 |
| GSM1132532 |
Cbx4 siRNA cumulus cell, biological rep. 1 |
| GSM1132533 |
Cbx4 siRNA cumulus cell, biological rep. 2 |
| GSM1132534 |
Cbx4 siRNA cumulus cell, biological rep. 3 |
| GSM1132535 |
Cbx4 siRNA cumulus cell, biological rep. 4 |
|
| Relations |
| BioProject |
PRJNA200970 |
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