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Series GSE46306 Query DataSets for GSE46306
Status Public on Jan 06, 2014
Title Genome-wide DNA methylation in cervical tissue
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary The aim of this study was to identify new candidate genes that are differentially methylated in squamous cell carcinoma compared to the DNA samples from cervical intraepithelial neoplasia grade 3 (CIN3) and normal cervical scrapes. The Illumina Infinium Human Methylation 450 K BeadChip method identifies genome-wide DNA methylation changes in CpG islands, CpG shores and shelves.
Overall design In this study 20 normal cervical samples (HPV negative), 18 samples with CIN3 lesions (HPV positive) and 6 cervical cancer tissues (HPV positive) were included.
Contributor(s) Farkas SA, Milutin-Gašperov N, Grce M, Nilsson TK
Citation(s) 24030264
Submission date Apr 23, 2013
Last update date Mar 22, 2019
Contact name Sanja A Farkas
Organization name Örebro University hospital
Department Laboratory medicine
Street address Södra rosen grevsgatan
City Örebro
ZIP/Postal code 701 85
Country Sweden
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (44)
GSM1128470 NT2_2008216.1_1R01C01
GSM1128471 NT2_2009033.1_1R01C02
GSM1128472 NT2_2008218.1_1R02C01
BioProject PRJNA198713

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE46306_Matrix_processed2.txt.gz 191.6 Mb (ftp)(http) TXT
GSE46306_Matrix_signal_intensities2.txt.gz 379.9 Mb (ftp)(http) TXT
GSE46306_RAW.tar 183.1 Mb (http)(custom) TAR
Processed data included within Sample table
Processed data are available on Series record

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