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Series GSE46097 Query DataSets for GSE46097
Status Public on Feb 24, 2014
Title Expression data of Participants of Ornish intervention and Control group
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Intensive lifestyle modification is believed to mediate cardiovascular disease (CVD) risk through traditional pathways that affect endothelial function and progression of atherosclerosis; however, the extent, persistence, and clinical significance of molecular change during lifestyle modification are not well known. Our study reveals that gene expression signatures are significantly modulated by rigorous lifestyle behaviors and track with CVD risk profiles over time.
Overall design We examined the impact of a rigorous CVD risk reduction program on peripheral blood gene expression profiles in 63 participants and 63 matched controls to characterize molecular response to lifestyle modification and identify regulatory pathways important to cardiovascular health.
Contributor(s) Ellsworth DL, Croft DT Jr, Weyandt J, Sturtz LA, Blackburn HL, Mamula KA, Vernalis MN
Citation(s) 24563419, 26484175
Submission date Apr 16, 2013
Last update date Jul 29, 2019
Contact name Darrell Ellsworth
Organization name Windber Research Institute
Street address 620 Seventh St.
City Windber
State/province PA
ZIP/Postal code 15963
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (378)
GSM1123226 Matched Ornish Participant [cv000288 baseline]
GSM1123227 Matched Ornish Participant [cv000288 3month]
GSM1123228 Matched Ornish Participant [cv000288 1year]
BioProject PRJNA197271

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE46097_RAW.tar 741.9 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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