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Series GSE45758 Query DataSets for GSE45758
Status Public on Apr 04, 2013
Title Expression Data from 24 orthotopic tumors grown in the pancreas of mice +/- MEK inhibitor PD0325901
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.
We used microarrays to find gene expression patterns associated with drug response and also identified genes regulated by the MAP kinase pathway
Overall design 6 pancreatic cell lines were injected into the pancreas of nude mice and treated either with vehicle control or PD0325901 for 12 plus 12 hours.
Contributor(s) Gysin S, Paquette J, McMahon M
Citation(s) 22833572
Submission date Apr 03, 2013
Last update date Dec 06, 2018
Contact name Stephan Christoph Gysin
Organization name UCSF
Department HDFCCC
Lab McCormick
Street address 1450 3rd Street
City San Francisco
State/province California
ZIP/Postal code 94158
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (24)
GSM1113812 MIAPaCa-2 #1, vehicle
GSM1113813 MIAPaCa-2 #2, vehicle
GSM1113814 MIAPaCa-2 #3, vehicle
This SubSeries is part of SuperSeries:
GSE45765 Expression Data from pancreatic cancer cell lines and orthotopic tumors grown with and without MEK inhibitor
BioProject PRJNA196178

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45758_RAW.tar 57.3 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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