|
| Status |
Public on Dec 17, 2014 |
| Title |
Anti-BRAF mutation drug resistance enhances EGFR expression in melanomas [methylation profiling] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
We treated melanoma cells with BRAF mutation with BRAF inhibitor and screened for BRAF inhibitor resistant cells. We extracted DNA from parental cells and resistant cell lines. We compared the DNA methylation via Illumina 450K Methylation Array
|
| |
|
| Overall design |
Bisulphite converted DNA from the 4 specimens was hybridised to the Illumina Infinium 450k Human Methylation Beadchip
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| |
|
| Contributor(s) |
Hoon D, Wang J |
| Citation(s) |
25243790 |
| Submission date |
Mar 30, 2013 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Dave S.B. Hoon |
| E-mail(s) |
hoond@jwci.org
|
| Organization name |
Saint John's Cancer Institute
|
| Department |
Translational Molecular Medicine
|
| Street address |
2200 Santa Monica Boulevard
|
| City |
Santa Monica |
| State/province |
CA |
| ZIP/Postal code |
90403 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
|
| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE45649 |
Anti-BRAF mutation drug resistance enhances EGFR expression in melanomas |
|
| Relations |
| BioProject |
PRJNA195562 |
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