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Series GSE45647 Query DataSets for GSE45647
Status Public on Dec 17, 2014
Title Anti-BRAF mutation drug resistance enhances EGFR expression in melanomas [methylation profiling]
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary We treated melanoma cells with BRAF mutation with BRAF inhibitor and screened for BRAF inhibitor resistant cells. We extracted DNA from parental cells and resistant cell lines. We compared the DNA methylation via Illumina 450K Methylation Array
Overall design Bisulphite converted DNA from the 4 specimens was hybridised to the Illumina Infinium 450k Human Methylation Beadchip
Contributor(s) Hoon D, Wang J
Citation(s) 25243790
Submission date Mar 30, 2013
Last update date Mar 22, 2019
Contact name Dave S.B. Hoon
Organization name Saint John's Cancer Institute
Department Translational Molecular Medicine
Street address 2200 Santa Monica Boulevard
City Santa Monica
State/province CA
ZIP/Postal code 90403
Country USA
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (4)
GSM1111251 Melanoma_Parental_1 [methylation]
GSM1111252 Melanoma_Resistant_1 [methylation]
GSM1111253 Melanoma_Parental_2 [methylation]
This SubSeries is part of SuperSeries:
GSE45649 Anti-BRAF mutation drug resistance enhances EGFR expression in melanomas
BioProject PRJNA195562

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45647_RAW.tar 183.1 Mb (http)(custom) TAR
GSE45647_signals.txt.gz 19.3 Mb (ftp)(http) TXT
Processed data included within Sample table

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