|
Status |
Public on Apr 29, 2014 |
Title |
MiR-155 promotes blood-brain barrier dysfunction in neuroinflammation (part 1) |
Organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by array
|
Summary |
Here, we investigated the time-course changes in the pattern of microRNA (miRNA) expression of TNFα and IFNγ-stimulated and unstimulated hCMEC/D3 cells, an immortalized human cerebral microvascular endothelial cell line.
|
|
|
Overall design |
In order to investigate pro-inflammatory cytokine-induced changes in miRNA levels in hCMEC/D3 cells, we challenged brain endothelial cells with TNFα and IFNγ (100 ng/ml) for 2 h, 6 h and 24 h and determined microRNA expression in cytokine-stimulated and unstimulated cells
|
|
|
Contributor(s) |
Lopez-Ramirez MA, Wu D, Pryce G, Simpson JE, Reijerkerk A, King-Robson J, Kay O, de Vries HE, Hirst MC, Sharrack B, Baker D, Male DK, Michael GJ, Romero IA |
Citation(s) |
24604078, 27246706 |
|
Submission date |
Feb 26, 2013 |
Last update date |
Oct 03, 2019 |
Contact name |
Miguel Alejandro Lopez-Ramirez |
E-mail(s) |
malopezramirez@ucsd.edu
|
Phone |
858-822-6487
|
Organization name |
University of California, San Diego
|
Department |
School of Medicine
|
Street address |
9500 Gilman Drive
|
City |
La Jolla |
State/province |
California/San Diego |
ZIP/Postal code |
92093 |
Country |
USA |
|
|
Platforms (1) |
GPL14767 |
Agilent-021827 Human miRNA Microarray G4470C (Feature Number version) |
|
Samples (18)
|
|
This SubSeries is part of SuperSeries: |
GSE44694 |
MiR-155 promotes blood-brain barrier dysfunction in neuroinflammation |
|
Relations |
BioProject |
PRJNA191030 |