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Series GSE44667 Query DataSets for GSE44667
Status Public on Jun 21, 2013
Title DNA methylation in Early Onset Preeclamptic placentas
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary We investigated the DNA methylation and gene expression of 20 chorionic villi samples from early onset preeclampsia placentas to 20 gestational age matched controls. From this we were able to see a widespread disregulation in DNA methylation across a subset of genes in the genome. This may help to elucidate the underlying biological problems that lead to early onset preeclampsia. We noted that there were DNA methylation changes in many genes of importance as well as in different genomic elements such as enhancers.
Overall design Bisulfite converted DNA from 20 third trimester early onset preeclampsia placentas and 20 gestational age matched controls
Contributor(s) Blair JD, Yuen RK, von Dadelszen P, Robinson WP
Citation(s) 23770704
Submission date Feb 26, 2013
Last update date Mar 22, 2019
Contact name Wendy Robinson
Organization name University of British Columbia
Department Medical Genetics
Lab Robinosn
Street address 950 W 28th Ave
City Vancouver
State/province BC
ZIP/Postal code V5Z 4H4
Country Canada
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (40)
GSM1088602 ChorionicVilli_EOPET_1 (methylation)
GSM1088603 ChorionicVilli_EOPET_2 (methylation)
GSM1088604 ChorionicVilli_EOPET_3 (methylation)
This SubSeries is part of SuperSeries:
GSE44712 Early-Onset Preeclampsia Placentas and Controls
BioProject PRJNA191068

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE44667_RAW.tar 183.1 Mb (http)(custom) TAR
GSE44667_signals.txt.gz 94.1 Mb (ftp)(http) TXT
Processed data included within Sample table

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