|
| Status |
Public on May 06, 2013 |
| Title |
Genome-scale DNA methylation maps of mouse chromaffin cells with or without Sdhb knock-out. |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
We report the analysis of DNA methylation in mouse chromaffin cell lines using reduced representation bisulfite sequencing (RRBS). We compared DNA methylation profiles of cell lines with or without a knock-out of Sdhb gene, showing that Sdhb disruption results in a hypermethylator phenotype.
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| |
|
| Overall design |
Reduced representation bisulfite sequencing of 4 mouse chromaffin cell samples (2 Sdhb wild-type and 2 Sdhb knock-out).
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| |
|
| Contributor(s) |
Letouzé E, Gimenez-Roqueplo A, Favier J |
| Citation(s) |
23707781 |
| Submission date |
Feb 15, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Eric Letouzé |
| E-mail(s) |
Eric.letouze@inserm.fr
|
| Organization name |
Ligue Contre Le Cancer
|
| Lab |
Centre de Recherche des Cordeliers
|
| Street address |
15 rue de l'école de médecine
|
| City |
Paris |
| ZIP/Postal code |
75006 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE43298 |
Genome-scale methylome profiling of human pheochromocytomas and paragangliomas (Illumina methylation beadchips) and mouse chromaffin cells (RRBS) |
|
| Relations |
| SRA |
SRP018700 |
| BioProject |
PRJNA189668 |
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