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Series GSE43916 Query DataSets for GSE43916
Status Public on Oct 24, 2013
Title Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary Here we reveal a hierarchical mechanism in the direct conversion of fibroblasts into induced neuronal (iN) cells mediated by the transcription factors Ascl1, Brn2, and Myt1l.
Overall design Examination of global transcriptional changes and mapping genome-wide transcription factors occupancy at distinct time points during the transdifferentiation process
Contributor(s) Wapinski OL, Qu K, Chang HY, Wernig M
Citation(s) 24243019
Submission date Jan 30, 2013
Last update date May 15, 2019
Contact name Kun Qu
Organization name Stanford University
Department Dermatology
Lab Howard Chang
Street address 269 Campus Dr. CCSR 2150
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
Platforms (3)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
GPL15103 Illumina HiSeq 1000 (Mus musculus)
Samples (38)
GSM1074345 MEFs_rtTA_Rep1
GSM1074346 MEFs_rtTA_Rep2
GSM1074347 MEFs+Ascl1_48hrs_Rep1
SRA SRP018305
BioProject PRJNA188177

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Supplementary file Size Download File type/resource
GSE43916_Ascl1_BAM_48hrs_summits.bed.gz 41.9 Kb (ftp)(http) BED
GSE43916_Ascl1_MEF_48hrs_summits.bed.gz 49.0 Kb (ftp)(http) BED
GSE43916_Ascl1_NHDF_summits.bed.gz 53.3 Kb (ftp)(http) BED
GSE43916_Ascl1_NHEK_summits.bed.gz 73.4 Kb (ftp)(http) BED
GSE43916_Ascl1_NPC_summits.bed.gz 81.5 Kb (ftp)(http) BED
GSE43916_rnaseq_rpkm_iN_mm9_refseq_genes_collapse.txt.gz 2.1 Mb (ftp)(http) TXT
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Processed data are available on Series record

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