|
Status |
Public on Oct 24, 2013 |
Title |
Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons |
Organisms |
Homo sapiens; Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
Here we reveal a hierarchical mechanism in the direct conversion of fibroblasts into induced neuronal (iN) cells mediated by the transcription factors Ascl1, Brn2, and Myt1l.
|
|
|
Overall design |
Examination of global transcriptional changes and mapping genome-wide transcription factors occupancy at distinct time points during the transdifferentiation process
|
|
|
Contributor(s) |
Wapinski OL, Qu K, Chang HY, Wernig M |
Citation(s) |
24243019 |
Submission date |
Jan 30, 2013 |
Last update date |
May 15, 2019 |
Contact name |
Kun Qu |
E-mail(s) |
kqu@stanford.edu
|
Organization name |
Stanford University
|
Department |
Dermatology
|
Lab |
Howard Chang
|
Street address |
269 Campus Dr. CCSR 2150
|
City |
Stanford |
State/province |
CA |
ZIP/Postal code |
94305 |
Country |
USA |
|
|
Platforms (3) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
GPL15103 |
Illumina HiSeq 1000 (Mus musculus) |
|
Samples (38)
|
|
Relations |
SRA |
SRP018305 |
BioProject |
PRJNA188177 |