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Series GSE43831 Query DataSets for GSE43831
Status Public on Feb 02, 2013
Title GATA factors efficiently direct cardiac fate from ESCs
Organism Mus musculus
Experiment type Expression profiling by array
Summary Gata5 efficiently promotes cardiomyocyte fate from murine ESCs.By removing serum from the culture conditions, GATA4 and GATA6 are each also able to efficiently promote cardiogenesis in ESC derivatives, with some distinctions. Thus, GATA factors can function in ESC derivatives upstream of other cardiac transcription factors to direct specification of progenitors with cardiac potential.
We used microarray to compared the global gene expression of Gata5-induced cardiac cells with other growth factor directed ESC-derived cardiac cells
 
Overall design iGata5 ESCs were induced with doxycycline at day 4 and harvested at day16 for RNA extraction and hybridization on Affymetrix microarrays.
 
Contributor(s) Turbendian HK, Gordillo M, Tsai S, Lu J, Kang G, Liu T, Tang A, Liu S, Fishman GI, Evans T
Citation(s) 23487308
Submission date Jan 28, 2013
Last update date Feb 11, 2019
Contact name Todd Evans
E-mail(s) tre2003@med.cornell.edu
Organization name Weill Medical College of Cornell University
Street address 1300 York Avenue Box 282
City New York
State/province New York
ZIP/Postal code 10065
Country USA
 
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (1)
GSM1071842 Day16 Gata5-induced cardiac cells
Relations
BioProject PRJNA188325

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE43831_RAW.tar 16.9 Mb (http)(custom) TAR (of CEL, CHP)
Processed data provided as supplementary file
Processed data included within Sample table

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