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Status |
Public on Mar 24, 2016 |
Title |
Response to Neoadjuvant Chemotherapy in Triple Negative Breast tumors. |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
In a cohort study of 7 women with primary invasive breast cancer, we obtained a tumor specimen before (biopsy) and after (tumorectomy) 4 cycles of NAC with epirubicine and cyclophosphamide, followed by 4 cycles of taxanes. Total RNA was extracted from tumor specimens and the whole transcriptome was quantified with Affymetrix HuGene1.1ST. Molecular functions changing during chemotherapy were searched.
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Overall design |
Whole genome expression of triple negative breast cancer tissues were measured before and after four cycles neoadjuvant chemotherapy
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Contributor(s) |
Gruosso T, Kieffer Y, Mechta-Grigoriou F |
Citation(s) |
27006338 |
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Submission date |
Jan 28, 2013 |
Last update date |
Nov 08, 2016 |
Contact name |
Fatima Mechta-Grigoriou |
E-mail(s) |
fatima.mechta-grigoriou@curie.fr
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Phone |
+33156246653
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Fax |
+33156246650
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Organization name |
Institut Curie
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Department |
INSERM U830
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Lab |
"Stress and Cancer" Lab.
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Street address |
26 rue d'Ulm
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City |
PARIS |
ZIP/Postal code |
75248 |
Country |
France |
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Platforms (1) |
GPL11532 |
[HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version] |
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Samples (14)
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Relations |
BioProject |
PRJNA187494 |