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Series GSE4315 Query DataSets for GSE4315
Status Public on Mar 02, 2006
Title Expression profiling of human endomyocardial biopsies before, during and after cardiac allograft rejection
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Cardiac allograft rejection remains a significant clinical problem in the early phase after heart transplantation and requires frequent surveillance with endomyocardial biopsy.
Endomyocardial tissue samples were obtained in connection with clinical biopsies from twenty consecutive heart transplant patients followed for six months. A rejection episode was observed in 14 patients and biopsies obtained before, during and after the episode were identified. Endomyocardial RNA, from three patients, matching these three points in time were analysed with DNA microarray.
Keywords: time course
Overall design Three subjects (subject number 1,8 and 12)
Three timepoints (Before, during and after an rejection episode)
Contributor(s) Karason K, Jernås M, Hägg DA, Svensson P
Citation(s) 16780603
Submission date Mar 01, 2006
Last update date Aug 10, 2018
Contact name Per-Arne Svensson
Phone +46 31 3426736
Organization name institute of medicine
Department Department of molecular and clinical medicine
Lab lab 13, w-lab
Street address Vitastraket12
City Gothenburg
ZIP/Postal code 41345
Country Sweden
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (9)
GSM98603 endomyocardial biopsies_subject1_before-rejection
GSM98614 endomyocardial biopsies_subject1_during-rejection
GSM98616 endomyocardial biopsies_subject1_after-rejection
BioProject PRJNA94853

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