|
| Status |
Public on Mar 02, 2006 |
| Title |
Expression profiling of human endomyocardial biopsies before, during and after cardiac allograft rejection |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Cardiac allograft rejection remains a significant clinical problem in the early phase after heart transplantation and requires frequent surveillance with endomyocardial biopsy.
Endomyocardial tissue samples were obtained in connection with clinical biopsies from twenty consecutive heart transplant patients followed for six months. A rejection episode was observed in 14 patients and biopsies obtained before, during and after the episode were identified. Endomyocardial RNA, from three patients, matching these three points in time were analysed with DNA microarray.
Keywords: time course
|
| |
|
| Overall design |
Three subjects (subject number 1,8 and 12)
Three timepoints (Before, during and after an rejection episode)
|
| |
|
| Contributor(s) |
Karason K, Jernås M, Hägg DA, Svensson P |
| Citation(s) |
16780603 |
| |
| Submission date |
Mar 01, 2006 |
| Last update date |
Aug 10, 2018 |
| Contact name |
Per-Arne Svensson |
| E-mail(s) |
per-arne.svensson@medic.gu.se
|
| Phone |
+46 31 3426736
|
| Organization name |
institute of medicine
|
| Department |
Department of molecular and clinical medicine
|
| Lab |
lab 13, w-lab
|
| Street address |
Vitastraket12
|
| City |
Gothenburg |
| ZIP/Postal code |
41345 |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
|
| Samples (9)
|
| GSM98603 |
endomyocardial biopsies_subject1_before-rejection |
| GSM98614 |
endomyocardial biopsies_subject1_during-rejection |
| GSM98616 |
endomyocardial biopsies_subject1_after-rejection |
| GSM98617 |
endomyocardial biopsies_subject12_before-rejection |
| GSM98618 |
endomyocardial biopsies_subject12_during-rejection |
| GSM98619 |
endomyocardial biopsies_subject12_after-rejection |
| GSM98620 |
endomyocardial biopsies_subject8_before-rejection |
| GSM98621 |
endomyocardial biopsies_subject8_during-rejection |
| GSM98623 |
endomyocardial biopsies_subject8_after-rejection |
|
| Relations |
| BioProject |
PRJNA94853 |
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