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Series GSE42991 Query DataSets for GSE42991
Status Public on Feb 01, 2013
Title Gene expression profiles of Tet1 knockout (T1KO), Tet2 knockout (T2KO) and Tet1/Tet2 double knockout (DKO) mouse embryonic stem cells.
Organism Mus musculus
Experiment type Expression profiling by array
Summary Global gene expression profile of single and double mutant mouse ES cells were compared to wt ES cells. Two male Tet1 KO, one male Tet2 KO, two male double KO, two female double KO, two male WT and two female WT mouse ES cells were compared.
 
Overall design Global gene expression profile of single and double knockout mouse embryonic stem cells were compared to that of wild type mouse ES cells. All used ES lines were derived from C57/BL/6 mixed background mice. RNA from feeder free mutant mouse ES cells was competetively hybridized against RNA from WT ES cells. Same sex lines were compared. Two independent ES line of each genotype were used, with the exception of Tet2 KO ES cells where only one male line was used.
 
Contributor(s) Barrasa MI, Dawlaty MM, Jaenisch R
Citation(s) 23352810
Submission date Dec 18, 2012
Last update date Nov 01, 2017
Contact name Inmaculada Barrasa
E-mail(s) wibr-bioinformatics@wi.mit.edu
Organization name Whitehead Institute
Street address Nine Cambridge Center
City Cambridge
State/province MA
ZIP/Postal code 02142
Country USA
 
Platforms (1)
GPL11202 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)
Samples (10)
GSM1054583 male DKO#51 versus male WT#6 Replicate 1
GSM1054584 male DKO#51 versus male WT#6 Replicate 2
GSM1054585 male DKO#61 versus male WT#92 Replicate 1
Relations
BioProject PRJNA184026

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE42991_RAW.tar 153.3 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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