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| Status |
Public on Nov 20, 2013 |
| Title |
Hdac6 regulates Tip60-p400 function in stem cells (gene expression) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To identify the functional role of Hdac6 in embryonic stem cells, we examined gene expression changes in mouse ES cells upon Tip60, Hdac6 and double knockdown.
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| Overall design |
Two biological replicates each for control (GFP), Tip60, Hdac6 and double KD in E14 mouse ESCs. Lentiviral-based shRNA was used and gene expression changes were determined 3 days after KD. The global gene expression profiles of Tip60, Hdac6 and double KD were compared to control KD cells.
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| Contributor(s) |
Chen PB, Hung J, Hickman TL, Coles AH, Carey JF, Weng Z, Chu F, Fazzio TG |
| Citation(s) |
24302573 |
| Submission date |
Nov 09, 2012 |
| Last update date |
Jan 19, 2018 |
| Contact name |
Benson Chen |
| E-mail(s) |
b5chen@ucsd.edu
|
| Organization name |
UC San Diego
|
| Department |
Cellular and Molecular Medicine
|
| Lab |
Bing Ren
|
| Street address |
9500 Gilman Dr. CMM East, Room 2071
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92093-0653 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL10333 |
Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version) |
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| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE42329 |
Hdac6 regulates Tip60-p400 function in stem cells |
|
| Relations |
| BioProject |
PRJNA181060 |
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