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Series GSE4119 Query DataSets for GSE4119
Status Public on Mar 16, 2006
Title Expression profiling of acute megakaryoblastic leukemia
Organism Homo sapiens
Experiment type Expression profiling by array
Summary mononuclear cells were isolated on a density gradient and RNA extracted using Trizol and the Promega SV column RNA purification. Affymetrix U133A chips were hybridised using standard procedures at the core facility of Dana Farber Cancer Institute.
Keywords: disease state analysis
Overall design This series includes samples of acute megakaryoblastic leukemia from 24 patients with Down Syndrome, 28 patients without Down Syndrome, 9 samples with acute myelomonocytic leukemia of patients without Down Syndrome, 8 samples from neonates with Down Syndrome and with transient myeloproliferative disease
Contributor(s) Bourquin J, Orkin SH
Citation(s) 16492768
Submission date Jan 30, 2006
Last update date Aug 10, 2018
Contact name Jean-Pierre Bourquin
Phone +41 44 266 7304
Fax +41 44 266 7171
Organization name University Children's Hospital Zurich
Department Pediatric Oncology
Lab Molecular Oncology
Street address Steinwiesstrasse 75
City Zurich
ZIP/Postal code 8032
Country Switzerland
Platforms (1)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
Samples (80)
GSM94221 AMKL patient sample_AMKL024
GSM94222 AMKL patient sample_AMKL025
GSM94223 AMKL patient sample_AMKL026
BioProject PRJNA95033

Sample information header descriptions
Down Syndrome Status
% Blast

Data table
Sample Down Syndrome Status Class Age Sex Source % Blast GATA1 Consequence Notes
24 non-DS AMKL 51 months M PB 58 nd
28 non-DS AMKL 8 months F BM 57 nd
29 non-DS AMKL 11 years M BM 46 nd
31 non-DS AMKL 13 months M BM 53 nd
33 non-DS AMKL 16 months M BM 31 wt
35 non-DS AMKL 20 months F BM 73 wt
36 non-DS AMKL 30 months M PB 80 wt Patient 49 at relapse
49 non-DS AMKL 11 months M BM 80 wt
37 non-DS AMKL 36 months M PB 74 wt
38 non-DS AMKL 24 months F PB 60 wt
40 non-DS AMKL 20 months F BM 70 nd
41 non-DS AMKL 7 months M BM 47 wt
44 non-DS AMKL 8 months M BM n.a wt
45 non-DS AMKL 3 months M BM 73 wt
46 non-DS AMKL 26 years M BM 15 wt
47 non-DS AMKL 38 months M BM 72 nd
48 non-DS AMKL 62 years F BM 75 wt
50 non-DS AMKL 18 month M BM 94 wt
54 non-DS AMKL 40 years F BM 42 nd
66 non-DS AMKL 14 months F PB 83 wt

Total number of rows: 72

Table truncated, full table size 3 Kbytes.

Download family Format
SOFT formatted family file(s) SOFTHelp
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Supplementary data files not provided

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