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Series GSE41011 Query DataSets for GSE41011
Status Public on Sep 30, 2015
Title Dynamic Transcriptome Analysis Reveal New Prognosis Biomarker in Colorectal Cancer (gene expression)
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Global gene profile of TNM-specific sequence design and integrated network-based bioinformatic analysis in 20 Colorectal cancer patients(n=5 for each TNM stage) are carried out to find the dynamic gene expression pattern specific to TNM stage. microRNA microrray experiment of the same samples were also performed. Two different platform of microarray data were analyzed together to uncover the potential biomarker for progression of colorectal cancer.
Overall design Primary tumor and paired distant normal mucosa of 20 colorectal patient were collected to performed the microarray experiment. Data of five classes including 12 distant normal mucosa,5 stage I, 4 stage II, 5 stage III and 5 stage IV tumor sample(Total of 31 samples) passed the correlation-based data filtering and went for further analysis. Gene expression pattern in accordance with TNM stage were analyzed to uncover the dynamic gene expression pattern. Significant expression patterns with distinct biological features were uncovered for prognosis prediction and further functional experiment.
Contributor(s) Li X
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Submission date Sep 19, 2012
Last update date Sep 30, 2015
Contact name xiayu li
Organization name Xiangya third hospital
Department department of gastroenterology
Lab Provincial key lab of non-resolving inflammation and cancer
Street address Yuelu district, Tongzipo road #138
City Changsha
State/province Hunan
ZIP/Postal code 410013
Country China
Platforms (1)
GPL6254 Phalanx Human OneArray
Samples (31)
GSM1006732 distant normal_stage 1_#1
GSM1006733 distant normal_stage 1_#3
GSM1006734 distant normal_stage 1_#4
This SubSeries is part of SuperSeries:
GSE41015 Dynamic Transcriptome Analysis Reveal New Prognosis Biomarker in Colorectal Cancer
BioProject PRJNA175533

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41011_phalanx_raw_lixiayu.txt.gz 5.9 Mb (ftp)(http) TXT
Processed data included within Sample table

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