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Series GSE40955 Query DataSets for GSE40955
Status Public on Oct 09, 2013
Title Allele-specific Methylation of Human Placental Tissue
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Summary In this study, we screened human placental samples for allele-specific methylation and subsequently novel imprinted genes associated with these regions. We used reduced representation bisulfite sequencing to identify partially methylated CpG islands (CGIs) in the human placental genome. We were able to delineate potential candidates for allele-specific methylation based on the calculation of a concordance statistic. Amongst the 28 regions chosen for validation based on high levels of expression, two regions were shown to exhibit allele-specific expression.
Overall design Single base-resolution methylation analysis in the placental genome and RNA-Seq
Contributor(s) Ding C
Citation(s) 24094292
Submission date Sep 18, 2012
Last update date May 15, 2019
Contact name Chunming Ding
Organization name Wenzhou Medical University
Street address School of Laboratory Medicine and Life Sciences
City Wenzhou
State/province Zhejiang
ZIP/Postal code 325035
Country China
Platforms (1)
GPL10999 Illumina Genome Analyzer IIx (Homo sapiens)
Samples (10)
GSM1005566 First trimester CVS 1T.1
GSM1005567 First trimester CVS 1T.2
GSM1005568 First trimester CVS 1T.3
SRA SRP015789
BioProject PRJNA175668

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Supplementary file Size Download File type/resource
GSE40955_100112_L1_RPKM_Das_GenRes_Processed_data2.txt.gz 380.3 Kb (ftp)(http) TXT
GSE40955_NP1T_Das_GenRes_Processed_data.txt.gz 13.1 Kb (ftp)(http) TXT
GSE40955_NP3T_Das_GenRes_Processed_data.txt.gz 13.7 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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