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Series GSE40870 Query DataSets for GSE40870
Status Public on Dec 18, 2012
Title Transient low-dose decitabine treatment of primary AML samples
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genome-wide DNA methylation profiling of primary AML samples treated with 100nM decitabine (DAC), cytarabine (AraC), or DMSO. Eight distinct AML samples were grown using an in vitro stromal co-culture system for 4 days and then treated with either DAC, Ara-C or DMSO for 3 days. DNA was prepared for genome-wide methylation analysis with the Illumina Infinium 450k Human DNA methylation BeadChip. DNA from each sample/treatment was analyzed on duplicate arrays.
Overall design Bisulfite-converted DNA from 24 samples was hybridised to the Illumina Infinium 450k Human Methylation Beadchip in duplicate (replicates are indicated by array plate number).
Contributor(s) Klco J, Spencer D
Citation(s) 23297133
Submission date Sep 13, 2012
Last update date Mar 22, 2019
Contact name Nobish Varghese
Organization name Washington University in St.Louis
Street address 4444 Forest Park Ave.
City StLouis
State/province MO
ZIP/Postal code 63110
Country USA
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (48)
GSM1003835 UPN 410324, 3 day AraC treatment, array plate number 3
GSM1003836 UPN 410324, 3 day AraC treatment, array plate number 7
GSM1003837 UPN 410324, 3 day DAC treatment, array plate number 3
This SubSeries is part of SuperSeries:
GSE40871 Gene expression and methylation profiling in primary AML cells treated with decitabine and cytarabine
BioProject PRJNA175142

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40870_RAW.tar 183.1 Mb (http)(custom) TAR
GSE40870_unmethylated_methylated_signals.txt.gz 271.5 Mb (ftp)(http) TXT
Processed data included within Sample table

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