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Series GSE40824 Query DataSets for GSE40824
Status Public on Sep 13, 2012
Title SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Comparing the host response of C57BL/6J mice to Tnfrsf1b knockouts in the same strain of mice.
Overall design Groups of 10-week-old C57BL/6 mice or Tnfrsf1b knockout mice were infected with SARS MA15 at a dose of 10^5 PFU or mock infected. Mice were euthanized on days 4 and 7 post-infection to measure virus load and isolate samples for measurement of virus load, lung pathology, transcriptional analysis and proteomics analysis. Mock-infected animals were also harvested at each time point. Mice were weighed every 24 hours to measure general disease progression and any mouse approaching 30% weight loss was euthanized.
Contributor(s) Baric R, Katze M, Gralinski L, Law L, Chang J
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Submission date Sep 12, 2012
Last update date Jan 12, 2017
Contact name Michael Katze
Organization name University of Washington
Department Microbiology
Lab Michael G. Katze, Ph.D
Street address Rosen Building 960 Republican St.
City Seattle
State/province WA
ZIP/Postal code 98109-4325
Country USA
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (22)
GSM1002567 SM019_1.1_B6_MA15_d4_1
GSM1002568 SM019_1.2_B6_MA15_d4_2
GSM1002569 SM019_1.3_B6_MA15_d4_3
BioProject PRJNA175045

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40824_RAW.tar 192.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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