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Series GSE40792 Query DataSets for GSE40792
Status Public on Sep 12, 2012
Title IM010 - Infection with A/Vietnam/1203/04 H5N1 influenza virus of C57BL/6J mice, IDO1 KO mice or TNFRSF1B KO mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Comparison of the host response to VN1203 infection in three different strains of mice: Wild-type C57BL/6J mice, IDO1 KO mice and TNFRSF1B KO.
Overall design Groups of 6-week-old mice were infected with A/Vietnam/1203/04 H5N1 influenza virus at a dose of 10^3 PFU or mock infected. Mice were euthanized on days 2 and 6 post-infection to measure virus load and isolate samples for measurement of virus load, lung pathology, transcriptional analysis and proteomics analysis. Mock-infected animals were also harvested at each time point. Mice were weighed every 24 hours to measure general disease progression and any mouse approaching 30% weight loss was euthanized.
Contributor(s) Kawaoka Y, Katze M, Eisfeld A, Law L, Chang J, Li C
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Submission date Sep 11, 2012
Last update date Jan 12, 2017
Contact name Michael Katze
Organization name University of Washington
Department Microbiology
Lab Michael G. Katze, Ph.D
Street address Rosen Building 960 Republican St.
City Seattle
State/province WA
ZIP/Postal code 98109-4325
Country USA
Platforms (1)
GPL7202 Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)
Samples (28)
GSM1001704 IM010_ID01 KO_Mock_2d_1
GSM1001705 IM010_ID01 KO_Mock_2d_2
GSM1001706 IM010_ID01 KO_Mock_2d_3
BioProject PRJNA174988

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE40792_RAW.tar 245.0 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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