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Series GSE39961 Query DataSets for GSE39961
Status Public on Jul 05, 2013
Title Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: PLZF_HEK]
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Within the overall project, we performed a set of microarray and chromatin-immunoprecipitation (ChIP)-chip experiments using siRNA against the (pro)renin receptor ((P)RR), stable overexpression of PLZF, the PLZF translocation inhibitor genistein and the specific V-ATPase inhibitor bafilomycin to dissect transcriptional pathways downstream of the (P)RR.
Overall design In this dataset, we include the expression data obtained from stable PLZF overexpression in HEK293T cells. Three intervention samples and three control samples were analyzed. We generated the following pairwise comparisons using Chipinspector (Genomatix Software GmbH) and a FDR of 1%.
ChipInspector carries out significance analysis on the single probe level. Normalized probe set level data not provided for individual Sample records. Processed data is available on Series record.
Contributor(s) Funke-Kaiser H, Zaade D
Citation(s) 23469216
Submission date Aug 08, 2012
Last update date Jan 25, 2019
Contact name Daniela Zaade
Phone 0049(0)30450525304
Organization name Charité
Department Center for Cardiovascular Research
Lab AG Heiko Funke-Kaiser
Street address Hessische Straße 3-4
City Berlin
ZIP/Postal code 10115
Country Germany
Platforms (1)
GPL10739 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [probe set (exon) version]
Samples (6)
GSM982314 HEK293T, stable PLZF overexpression, replica 1
GSM982315 HEK293T, stable transfection of insertless vector, replica 1
GSM982316 HEK293T, stable PLZF overexpression, replica 2
This SubSeries is part of SuperSeries:
GSE39965 Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses
BioProject PRJNA172169

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39961_FK_41-43-45_vs_42-44-46.txt.gz 16.2 Kb (ftp)(http) TXT
GSE39961_RAW.tar 26.3 Mb (http)(custom) TAR (of CEL)
Processed data are available on Series record

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