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Series GSE39768 Query DataSets for GSE39768
Status Public on Sep 12, 2012
Title Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Extra chromosome copies markedly alter the physiology of eukaryotic cells, but the underlying reasons are not well understood. We created human trisomic and tetrasomic cell lines and determined the quantitative changes in their genome, transcriptome and proteome in comparison to their diploid counterparts.
Overall design Aneuploid cell lines derived from HCT116 and RPE-1 cell lines were compared to their diploid counterparts; per study, 3 biological replicates have been performed.
Contributor(s) Silvia C, Gabriele S, Zuzana S
Citation(s) 22968442, 25205676
Submission date Jul 31, 2012
Last update date Nov 27, 2018
Contact name Gabriele Stoehr
Organization name MPI of Biochemistry
Department Proteomics ans Signaltransduction
Street address Am Klopferspitz 18
City Martinsried
ZIP/Postal code 82152
Country Germany
Platforms (2)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (18)
GSM978891 HCT116_WT_R1
GSM978892 HCT116_WT_R2
GSM978893 HCT116_WT_R3
BioProject PRJNA171695

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39768.xlsx.gz 2.5 Mb (ftp)(http) XLSX
GSE39768_RAW.tar 170.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
Processed data provided as supplementary file
Processed data are available on Series record

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