|
| Status |
Public on Apr 03, 2013 |
| Title |
tRNA fragment profiling in CLP1 mutant (kinase-dead) mice |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Loss of CLP1 activity results in the accumulation of novel sets of small RNA fragments derived from aberrant processing of tyrosine pre-tRNA. Such tRNA fragments sensitize cells to oxidative stress-induced p53 activation and p53-dependent cell death.
|
| |
|
| Overall design |
2 samples, Wt and Clp1(k/k), no replicates
|
| |
|
| Contributor(s) |
Hanada T, Weitzer S, Martinez J |
| Citation(s) |
23474986 |
| Submission date |
Jul 11, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Javier Martinez |
| Organization name |
IMBA
|
| Street address |
Dr. Bohr-Gasse 3
|
| City |
Vienna |
| ZIP/Postal code |
1030 |
| Country |
Austria |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (2) |
|
| Relations |
| BioProject |
PRJNA170450 |
| SRA |
SRP014197 |
