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Series GSE39224 Query DataSets for GSE39224
Status Public on Mar 31, 2013
Title Agilent microarray analysis between a Dullard-heterozygous and a Dullard-homozygous E7.5 embryo
Organism Mus musculus
Experiment type Expression profiling by array
Summary To explore the loss of Dullurd function in mouse embryo development, we have performed the Agilent microarray analysis between a Dullard-heterozygous and a Dullard-homozygous E7.5 embryo. Our findings show that Dullard does not act in concert with BMP4 and Smad1/5/8, whereas loss of Dullard is associated with a reduced level of WNT/β-catenin signaling activity, accompanied by elevated expression of Wnt3 and WNT antagonists including Dkk1, Sfrp1 and Sfrp5 in mouse germ cell formation.
Overall design E7.5 mouse embryos were collected. One Dullard-heterozygous embryo and one Dullard-homozygous embryo were used for the analysis.
Contributor(s) Tanaka SS
Citation(s) 23469192
Submission date Jul 10, 2012
Last update date Jan 19, 2018
Contact name Satomi S Tanaka
Organization name Kumamoto University
Department Institute of Molecular Embryology and Genetics
Lab Department of Kidney Development
Street address 2-2-1 Honjo
City Kumamoto
State/province Kumamoto
ZIP/Postal code 860-0811
Country Japan
Platforms (1)
GPL10333 Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version)
Samples (2)
GSM958331 Du-het
GSM958332 Du-mut
BioProject PRJNA170249

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39224_RAW.tar 10.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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