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Series GSE39189 Query DataSets for GSE39189
Status Public on Jul 10, 2012
Title GEP data from BCWM.1 cells treated with LNA antimiR-155 or scramble control
Organism Homo sapiens
Experiment type Expression profiling by array
Summary microRNA-155 acts as an oncogenic miRNA in B-cell lymphoproliferative disorders including Waldenstrom Macroglobulinemia (WM) and Chronic Lymphocytic Leukemia (CLL).
we used an 8-mer LNA (locked nucleic acid) phosphorothioate oligonucleotide targeting the seed region of miR-155 to effectively antagonize in vitro tumor growth in WM.
Overall design We performed gene expression profiling (GEP) analysis on BCWM.1 cells after treatment with LNA antimiR-155 or scramble control for 48 hours.
Contributor(s) Zhang Y, Ghobrial IM
Citation(s) 22797699
Submission date Jul 09, 2012
Last update date Dec 06, 2018
Contact name Yong Zhang
Organization name Dana-Farber Cancer Institute
Department Medical Oncology
Street address 450 Brookline Ave
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (2)
GSM957717 BCWM1-scr-48hr
GSM957718 BCWM1-anti155-48hr
BioProject PRJNA170178

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39189_RAW.tar 4.3 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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