|
Status |
Public on Jul 01, 2012 |
Title |
Analysis of Pro-Inflammatory Gene Activation and RNA Processing by RNAseq of Nascent Transcripts [supplement] |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
Note: These datasets are in supplement to, but separate from, Geo GSE32916. We examined pro-inflammatory gene activation in activated wildtype and IFNAR-/- murine macrophages by performing RNA-Seq with poly(A) enriched transcripts. This experimental strategy allowed a global, high-resolution analysis of the transcriptional regulation of diverse classes of co-expressed genes and allowed us to identify co-expressed gene classes that may depend on IFN-signaling for its expression. The results provide quantitative insights into the relationship between transcription and distinct promoter and chromatin properties.
|
|
|
Overall design |
RNA-seq of poly(A) enriched RNA from five stimulation time-points in wildtype and IFNAR-/- macrophages
|
|
|
Contributor(s) |
Smale ST, Tong A, Bhatt DM |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
Submission date |
Jun 22, 2012 |
Last update date |
Jan 25, 2024 |
Contact name |
Allison Daly |
E-mail(s) |
smale.geo.uploads@gmail.com
|
Organization name |
UCLA
|
Department |
MIMG
|
Lab |
Smale Lab
|
Street address |
6-730 MRL 675 Charles E. Young Drive South
|
City |
Los Angeles |
State/province |
Ca |
ZIP/Postal code |
90024 |
Country |
USA |
|
|
Platforms (1) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
Samples (10)
|
|
Relations |
BioProject |
PRJNA169142 |
SRA |
SRP013877 |