|
| Status |
Public on Jul 01, 2012 |
| Title |
Analysis of Pro-Inflammatory Gene Activation and RNA Processing by RNAseq of Nascent Transcripts [supplement] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Note: These datasets are in supplement to, but separate from, Geo GSE32916. We examined pro-inflammatory gene activation in activated wildtype and IFNAR-/- murine macrophages by performing RNA-Seq with poly(A) enriched transcripts. This experimental strategy allowed a global, high-resolution analysis of the transcriptional regulation of diverse classes of co-expressed genes and allowed us to identify co-expressed gene classes that may depend on IFN-signaling for its expression. The results provide quantitative insights into the relationship between transcription and distinct promoter and chromatin properties.
|
| |
|
| Overall design |
RNA-seq of poly(A) enriched RNA from five stimulation time-points in wildtype and IFNAR-/- macrophages
|
| |
|
| Contributor(s) |
Smale ST, Tong A, Bhatt DM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jun 22, 2012 |
| Last update date |
Jun 16, 2023 |
| Contact name |
Stephen Smale |
| E-mail(s) |
smale@mednet.ucla.edu
|
| Organization name |
UCLA
|
| Street address |
675 Charles E. Young Drive South
|
| City |
Los Angeles |
| ZIP/Postal code |
90095 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA169142 |
| SRA |
SRP013877 |
Less...
More...