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Series GSE38651 Query DataSets for GSE38651
Status Public on Jan 22, 2013
Title Dnmt3a protects active chromosome domains against cancer-associated hypomethylation
Organism Mus musculus
Experiment type Methylation profiling by high throughput sequencing
Summary The results of the study uncover conserved features of cancer methylomes and provide a mechanistic explanation for the tumor-promoting effects of Dnmt3a mutations.
Overall design Whole genome methylation analysis of Mus musculus. Five samples were analyzed, one control sample containing normal healthy lung tissue, two samples containing big (WTB) or small (WTS) Dnmt3a WT tumors, two samples containing big (KOB) or small (KOS) Dnmt3a knock-out tumors
Contributor(s) Lyko F, Jaenisch R
Citation(s) 23284304
Submission date Jun 12, 2012
Last update date May 15, 2019
Contact name Guenter Raddatz
Organization name German Center for Cancer Research
Street address Im Neuenheimer Feld 580
City Heidelberg
ZIP/Postal code 69120
Country Germany
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (5)
GSM946855 Healthy lung tissue
GSM946856 Big lung tumor tissue with Dnmt3a knocked out
GSM946857 Small lung tumor tissue with Dnmt3a knocked out
SRA SRP013702
BioProject PRJNA168371

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE38651_RAW.tar 960.2 Mb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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